News from CROI 2013

The 20th Conference on Retroviruses and Opportunistic Infections (CROI 2013) took place at the Georgia World Congress Center in Atlanta, USA, in early March 2013.

We reported on key research presented at the conference, publishing news and sending out summary bulletins by email, three during the conference week and one the following week.

CROI is a scientific conference, bringing together around 4000 researchers and doctors to share their work and debate current issues. As well as publishing abstracts and posters on the official conference website, the conference organisers film key sessions and produce webcasts, so you can watch presentations online. They aimed to make around 90% of the conference available online and we included relevant links in our news stories and bulletins.

“The coverage made me feel I was at the conference and I appreciate NAM's effort in sharing the bulletins.” NAM bulletin subscriber

aidsmap news from CROI 2013

Dually active antiretroviral therapy protects against hepatitis B infection

Use of antiretroviral therapy that includes drugs active against both hepatitis B virus (HBV) and HIV reduces the risk that people living with HIV will become infected

Published
07 March 2013
By
Liz Highleyman
Continuing cotrimoxazole in children on ART reduces the risk of hospitalisation

Children on ART for more than two years who continued taking daily cotrimoxazole had significantly fewer hospitalisations for malaria as well as for non-malarial infections (notably pneumonia, sepsis

Published
06 March 2013
By
Carole Leach-Lemens
Black gay men run higher risk of HIV infection despite fewer partners

An analysis of four studies of sexual risk and HIV infection in US gay men, presented at the 20th Conference on Retroviruses and Opportunistic Infections (CROI

Published
06 March 2013
By
Gus Cairns
New NNRTI MK-1439 shows promise in early clinical trial

A next-generation non-nucleoside reverse transcriptase inhibitor (NNRTI), MK-1439, demonstrated robust antiretroviral activity and good tolerability as monotherapy in a small phase Ib clinical study, researchers reported yesterday at the

Published
06 March 2013
By
Liz Highleyman
Dual CCR5/CCR2 inhibitor cenicriviroc has anti-inflammatory as well as anti-HIV effect

Cenicriviroc, which blocks both CCR5 and CCR2 receptors on immune cells, is effective against HIV, better tolerated than current antiretrovirals and has immunomodulatory activity that may reduce inflammation,

Published
06 March 2013
By
Liz Highleyman
Small risk of neurological birth defects due to efavirenz confirmed in French cohort

A large French study has found an elevated risk of some birth defects in children born to women exposed to some antiretroviral drugs during the first trimester

Published
06 March 2013
By
Keith Alcorn
HIV treatment for children is safe and highly effective without laboratory monitoring in large African trial

Children did just as well on antiretroviral therapy without routine laboratory monitoring of CD4 cell counts or drug side-effects as those who received regular monitoring during four

Published
05 March 2013
By
Keith Alcorn
French studies report real-world data on use of telaprevir and boceprevir in people with HIV and hepatitis C co-infection

Adding boceprevir or telaprevir to interferon-based therapy showed promising indications of efficacy and acceptable safety for difficult-to-treat HIV/HCV co-infected prior non-responders in a pair of French studies presented

Published
05 March 2013
By
Liz Highleyman
Very early antiretroviral treatment limits the size of HIV reservoir

Very early antiretroviral treatment may limit the size of the HIV reservoir in adults and children, according to studies presented on 4 March at the 20th Conference

Published
05 March 2013
By
Keith Alcorn
Sofosbuvir/ledipasvir/ribavirin cures 100% of genotype 1 hepatitis C patients

An interferon-free regimen containing sofosbuvir (formerly GS-7997), ledipasvir (formerly GS-5885) and ribavirin produced a 12-week post-treatment sustained virological response (SVR12) rate of 100% for both treatment-naive hepatitis C

Published
05 March 2013
By
Liz Highleyman
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  • Can people with drug-resistant #HIV omit NRTIs when switching from a failing regimen? http://dlvr.it/334k1m #CROI #CROI201307 Mar 2013 04:48
  • Here's the third of our #CROI bulletins. Among other things, news on #HIV, #TB and #HBV: http://bit.ly/WwG6OD #CROI201307 Mar 2013 03:25
  • Currently at #CROI2013 with poster. Thanks to all for participation and support.07 Mar 2013 12:48
  • Dually active antiretroviral therapy protects against hepatitis B infection #aids #hiv #hepB http://www.aidsmap.com/page/2590079/07 Mar 2013 06:40
  • Watching #CROI presentations, eating vegan pesto, and loving life #publichealth #nerd07 Mar 2013 03:55
  • I survived #CROI2013. Adding to the list of things that this former AIDS baby has done before turning 30. #thankyouscience #byebyegp12007 Mar 2013 01:11
  • A take home from #croi - rush for DAA now or wait for IFN-free therapy? Fibrosis assessment in #HIV #hepC co-infection crucial for decision.07 Mar 2013 12:38
  • One of the best presentations at #CROI2013. Beyrer on the global HIV in MSM epidemic http://webcasts.retroconference.org/console/player/19422?mediaType=audio07 Mar 2013 12:16
  • Behind the Miracle Cure a Broken System Lurks from @HIVPrevJustice http://rmdy.hm/iJu #hiv #aids #croi2013 #policy #healthcare06 Mar 2013 11:01
  • Alexander Pym - last lecture of #CROI- talking about how to make effective XDR treatment #worldTBday - watch it at http://retroconference.org06 Mar 2013 10:58
  • Alexander Pym #CROI asks are we over treating for MDRTB???06 Mar 2013 10:47
  • Soumya Swaminthan at #CROI2013 excellent presentation on TB in children and women,in children.06 Mar 2013 10:37
  • #CROI Exciting research into point of care viral load testing and early infant diagnosis. @Jhpiego @mchipnet06 Mar 2013 10:04
  • At #CROI conference center, these carts are EVERYWHERE. With 8 hrs of presentations a day, they know what we need. http://pic.twitter.com/fs25Sy3kFA06 Mar 2013 07:18
  • Continuing cotrimoxazole in children on ART reduces the risk of hospitalisation http://dlvr.it/32qdKt #CROI06 Mar 2013 03:57
  • If like me you didn't make it to Atlanta - this is pretty neat: http://webcasts.retroconference.org/ #CROI06 Mar 2013 03:55
  • I've seen several intriguing posters at #CROI that deserve more attention than they usually get (there's so many)! Hard to sum in 140 chars.06 Mar 2013 04:21
  • Slight increase in transmitted drug resistance in the US. Especially for NNRTIs #CROI201306 Mar 2013 03:59
  • Worrying pattern seen elsewhere too MT @aidsmap_news: Black MSM run higher risk of HIV despite fewer partners http://dlvr.it/32nZgz #CROI”06 Mar 2013 03:17
  • next lecture- substantial burden of non-AIDS cancers in PLHIV, from Pune India - Sheela Godbole #CROI06 Mar 2013 03:10
  • The second of our news summary bulletins from #CROI is now available online: http://bit.ly/WuGRYh #CROI2013 #HIV #HCV06 Mar 2013 02:45
  • Plenary this morning on attempting to cure HIV with gene modified stem cell transplants. #CROI201306 Mar 2013 02:32
  • from magic mountain to table mountain lecture just ended, sobering #CROI #worldTBday #tuberculosis video will be on http://retroconference.org06 Mar 2013 02:00
  • A.Diacon @ #CROI 2013: "Participants of MDR drug clinical trial need to be followed up up to 1 y following completion of study"06 Mar 2013 01:49
  • Black gay men run higher risk of HIV infection despite fewer partners http://dlvr.it/32nZgz #CROI06 Mar 2013 01:19
  • RT @DrFriedenCDC: CDC at #CROI: #HIV-infected adults with healthcare coverage are more likely to have their virus under control. http://go.usa.gov/22CA06 Mar 2013 12:52
  • Dual CCR5/CCR2 inhibitor cenicriviroc has anti-inflammatory as well as anti-HIV effect http://dlvr.it/32l1vp #CROI #CROI2013 #HIV06 Mar 2013 10:27
  • New NNRTI MK-1439 shows promise in early clinical trial http://dlvr.it/32l1zC #CROI06 Mar 2013 10:03
  • Today is a full #TB day at #CROI 2013 including a plenary talk, oral abstracts, poster sessions and a symposium.06 Mar 2013 09:06
  • Small risk of neurological birth defects due to efavirenz confirmed in French cohort http://dlvr.it/32hM9r #CROI06 Mar 2013 05:20
  • There was a good and necessary discussion today at #CROI2013 about making sure HIV sequence data is untraceable back to people.06 Mar 2013 05:00
  • HIV treatment for children is safe and highly effective without laboratory monitoring in large African trial http://dlvr.it/32gsR2 #CROI06 Mar 2013 04:15
  • #CROI video and slides -- Tuesday, 3/05/2013 -- http://bit.ly/W3TdnT06 Mar 2013 03:12
  • New interview with @whitehouse Office of Natl AIDS Policy Director Dr. Colfax discussing HIV research at #CROI: http://go.usa.gov/2bc306 Mar 2013 01:09
  • no magic bullet - building HIV prevention response for young women requires multiple levels of intervention - Sinead Delany-Moretilwe #CROI05 Mar 2013 10:16
  • The #CROI #HIV restriction factor discussion on TRIM5alpha has gotten quite feisty!05 Mar 2013 10:09
  • Gary Harper re: HIV behav & biomed synergy: "You can make the best HIV pill, but if I don't put it in my mouth, it won't work." #CROI201305 Mar 2013 09:52
  • Brilliant, beautiful plenary by Chris Beyrer on global #HIV epidemic in gay/bisex/otherMSM #CROI #CROI2013 Watch at http://bit.ly/WB8j1q05 Mar 2013 09:18
  • MSF at #CROI: "Viral load monitoring is still 1 of the best tools we have to stay one step ahead of the virus” http://ow.ly/ioazW #HIV05 Mar 2013 08:55
  • Great session on HIV, contraception and fertility intentions at #CROI @Jhpiego @mchipnet @AnnePfitzer05 Mar 2013 07:20
  • Julio Montaner at #CROI 'it's more than just money that keeps people from accessing care' #sdoh05 Mar 2013 07:12
  • exome sequencing of elite and rapid HIV progressors, results form the exploratory pilot of the UK HIV Genomics consortium #CROI @EricTopol05 Mar 2013 07:11
  • In 20 city CDC study, gay/bisexual men w/ HIV who were already aware of their infection increased from 56% in 2008 to 66% in 2011. #CROI05 Mar 2013 05:57
  • CDC at #CROI: #HIV prevalence in gay/bisexual men in 20 cities remained steady at <20% from 2008 to 201105 Mar 2013 05:39
  • Today's #CROI bulletin is now available in English, French, Spanish, Portuguese and Italian on our #CROI2013 pages: http://www.aidsmap.com/croi201305 Mar 2013 05:51
  • Cenicriviroc data looks nice -- lowers LDL too, daily dosing #CROI05 Mar 2013 05:13
  • #CROI ARROW trial reports benefit of cotrimoxazole for HIV+ kids even when on ART--less malaria, fewer hospitalizations @Jhpiego @mchipnet05 Mar 2013 04:37
  • We're watching out for new developments getting unveiled at #croi2013, some interesting breakthroughs being announced05 Mar 2013 04:34
  • Bulletin électronique en français sur les nouvelles de #CROI2013: http://bit.ly/VA3YiW #VIH #CROI05 Mar 2013 04:08
  • Black MSM are disproportionately affected by HIV and less aware of their status. GET TESTED #CROI201305 Mar 2013 03:40

NAM is partnering with gTt (Barcelona), GAT (Lisbon) and LILA (Como) to deliver the CROI 2013 bulletins, which have also been made possible thanks to support from Bristol-Myers Squibb. NAM’s wider conference news reporting services have been supported by Abbott, Boehringer Ingelheim, Janssen, Roche and ViiV Healthcare. The funders have no editorial control over the content of the materials.